Flow-regulated lymphatic vasculature development and signaling

The role of blood flow in regulating signaling pathways and gene expression in the blood vasculature is well known. Recent studies have identified equally important roles of flow-mediated signaling in the lymphatic circulation including control of lymphatic vascular growth, remodeling, regeneration...

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Detalles Bibliográficos
Autores principales: Wang, Yingdi, Simons, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105398/
https://www.ncbi.nlm.nih.gov/pubmed/25053993
http://dx.doi.org/10.1186/2045-824X-6-14
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author Wang, Yingdi
Simons, Michael
author_facet Wang, Yingdi
Simons, Michael
author_sort Wang, Yingdi
collection PubMed
description The role of blood flow in regulating signaling pathways and gene expression in the blood vasculature is well known. Recent studies have identified equally important roles of flow-mediated signaling in the lymphatic circulation including control of lymphatic vascular growth, remodeling, regeneration and maintenance of the lymphatic fate. In this review, we summarize these advances focusing on the role of fluid dynamics in control of lymphatic vasculature formation.
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spelling pubmed-41053982014-07-23 Flow-regulated lymphatic vasculature development and signaling Wang, Yingdi Simons, Michael Vasc Cell Review The role of blood flow in regulating signaling pathways and gene expression in the blood vasculature is well known. Recent studies have identified equally important roles of flow-mediated signaling in the lymphatic circulation including control of lymphatic vascular growth, remodeling, regeneration and maintenance of the lymphatic fate. In this review, we summarize these advances focusing on the role of fluid dynamics in control of lymphatic vasculature formation. BioMed Central 2014-07-09 /pmc/articles/PMC4105398/ /pubmed/25053993 http://dx.doi.org/10.1186/2045-824X-6-14 Text en Copyright © 2014 Wang and Simons; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/4.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review
Wang, Yingdi
Simons, Michael
Flow-regulated lymphatic vasculature development and signaling
title Flow-regulated lymphatic vasculature development and signaling
title_full Flow-regulated lymphatic vasculature development and signaling
title_fullStr Flow-regulated lymphatic vasculature development and signaling
title_full_unstemmed Flow-regulated lymphatic vasculature development and signaling
title_short Flow-regulated lymphatic vasculature development and signaling
title_sort flow-regulated lymphatic vasculature development and signaling
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105398/
https://www.ncbi.nlm.nih.gov/pubmed/25053993
http://dx.doi.org/10.1186/2045-824X-6-14
work_keys_str_mv AT wangyingdi flowregulatedlymphaticvasculaturedevelopmentandsignaling
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