Cargando…
Activated Platelets from Diabetic Rats Cause Endothelial Dysfunction by Decreasing Akt/Endothelial NO Synthase Signaling Pathway
Diabetes is associated with endothelial dysfunction and platelet activation, both of which may contribute to increased cardiovascular risk. The purpose of this study was to characterize circulating platelets in diabetes and clarify their effects on endothelial function. Male Wistar rats were injecte...
Autores principales: | Ishida, Keiko, Taguchi, Kumiko, Matsumoto, Takayuki, Kobayashi, Tsuneo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105471/ https://www.ncbi.nlm.nih.gov/pubmed/25047034 http://dx.doi.org/10.1371/journal.pone.0102310 |
Ejemplares similares
-
G Protein–Coupled Receptor Kinase 2, With β-Arrestin 2, Impairs Insulin-Induced Akt/Endothelial Nitric Oxide Synthase Signaling in ob/ob Mouse Aorta
por: Taguchi, Kumiko, et al.
Publicado: (2012) -
G-protein-coupled receptor kinase 2 and endothelial dysfunction: molecular
insights and pathophysiological mechanisms
por: Taguchi, Kumiko, et al.
Publicado: (2015) -
Suppression of GRK2 expression reduces endothelial dysfunction by restoring glucose homeostasis
por: Taguchi, Kumiko, et al.
Publicado: (2017) -
Acute Exposure to Indoxyl Sulfate Impairs Endothelium-Dependent Vasorelaxation in Rat Aorta
por: Matsumoto, Takayuki, et al.
Publicado: (2019) -
Perlecan deficiency causes endothelial dysfunction by reducing the expression of endothelial nitric oxide synthase
por: Nonaka, Risa, et al.
Publicado: (2015)