Claudin-1 overexpression in intestinal epithelial cells enhances susceptibility to adenamatous polyposis coli-mediated colon tumorigenesis

BACKGROUND: The tight junction protein Claudin-1, a claudin family member, has been implicated in several gastro-intestinal pathologies including inflammatory bowel disease (IBD) and colorectal cancer (CRC). In this regard, we have demonstrated that claudin-1 expression in colon cancer cells potenti...

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Detalles Bibliográficos
Autores principales: Pope, Jillian L, Ahmad, Rizwan, Bhat, Ajaz A, Washington, Mary K, Singh, Amar B, Dhawan, Punita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105545/
https://www.ncbi.nlm.nih.gov/pubmed/24997475
http://dx.doi.org/10.1186/1476-4598-13-167

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