Accumulation of V(H) Replacement Products in IgH Genes Derived from Autoimmune Diseases and Anti-Viral Responses in Human

V(H) replacement refers to RAG-mediated secondary recombination of the IgH genes, which renews almost the entire V(H) gene coding region but retains a short stretch of nucleotides as a V(H) replacement footprint at the newly generated V(H)–D(H) junction. To explore the biological significance of V(H...

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Detalles Bibliográficos
Autores principales: Lange, Miles D., Huang, Lin, Yu, Yangsheng, Li, Song, Liao, Hongyan, Zemlin, Michael, Su, Kaihong, Zhang, Zhixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105631/
https://www.ncbi.nlm.nih.gov/pubmed/25101087
http://dx.doi.org/10.3389/fimmu.2014.00345

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105631/
https://www.ncbi.nlm.nih.gov/pubmed/25101087
http://dx.doi.org/10.3389/fimmu.2014.00345

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