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Nonsense-mediated decay factors are involved in the regulation of selenoprotein mRNA levels during selenium deficiency
Selenoproteins contain the unique amino acid selenocysteine (Sec), which is encoded by the triplet UGA. Since UGA also serves as a stop codon, it has been postulated that selenoprotein mRNAs are targeted for degradation by the nonsense-mediated mRNA decay pathway (NMD). Several reports have observed...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory Press
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105750/ https://www.ncbi.nlm.nih.gov/pubmed/24947499 http://dx.doi.org/10.1261/rna.043463.113 |