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eIF4F-like complexes formed by cap-binding homolog TbEIF4E5 with TbEIF4G1 or TbEIF4G2 are implicated in post-transcriptional regulation in Trypanosoma brucei
Members of the eIF4E mRNA cap-binding family are involved in translation and the modulation of transcript availability in other systems as part of a three-component complex including eIF4G and eIF4A. The kinetoplastids possess four described eIF4E and five eIF4G homologs. We have identified two new...
Autores principales: | Freire, Eden R., Vashisht, Ajay A., Malvezzi, Amaranta M., Zuberek, Joanna, Langousis, Gerasimos, Saada, Edwin A., Nascimento, Janaína De F., Stepinski, Janusz, Darzynkiewicz, Edward, Hill, Kent, De Melo Neto, Osvaldo P., Wohlschlegel, James A., Sturm, Nancy R., Campbell, David A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105752/ https://www.ncbi.nlm.nih.gov/pubmed/24962368 http://dx.doi.org/10.1261/rna.045534.114 |
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