Brain-specific knockdown of miR-29 results in neuronal cell death and ataxia in mice

Several microRNAs have been implicated in neurogenesis, neuronal differentiation, neurodevelopment, and memory. Development of miRNA-based therapeutics, however, needs tools for effective miRNA modulation, tissue-specific delivery, and in vivo evidence of functional effects following the knockdown o...

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Detalles Bibliográficos
Autores principales: Roshan, Reema, Shridhar, Shruti, Sarangdhar, Mayuresh A., Banik, Arpita, Chawla, Mrinal, Garg, Manali, Singh, Vijay PAL, Pillai, Beena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105753/
https://www.ncbi.nlm.nih.gov/pubmed/24958907
http://dx.doi.org/10.1261/rna.044008.113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105753/
https://www.ncbi.nlm.nih.gov/pubmed/24958907
http://dx.doi.org/10.1261/rna.044008.113

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