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The RNA binding domain of Pumilio antagonizes poly-adenosine binding protein and accelerates deadenylation
PUF proteins are potent repressors that serve important roles in stem cell maintenance, neurological processes, and embryonic development. These functions are driven by PUF protein recognition of specific binding sites within the 3′ untranslated regions of target mRNAs. In this study, we investigate...
Autores principales: | Weidmann, Chase A., Raynard, Nathan A., Blewett, Nathan H., Van Etten, Jamie, Goldstrohm, Aaron C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105754/ https://www.ncbi.nlm.nih.gov/pubmed/24942623 http://dx.doi.org/10.1261/rna.046029.114 |
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