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The synergistic regulation of VEGF-mediated angiogenesis through miR-190 and target genes

VEGF is a major contributor to angiogenesis, a vital process in normal growth and development and tumor transition. However, the current clinical efficacy of VEGF inhibitors is limited, and the molecular mechanism underlying VEGF regulation remains to be elucidated. Here we show that miR-190 directl...

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Detalles Bibliográficos
Autores principales: Hao, Yang, Yang, Junyu, Yin, Shenyi, Zhang, Hanshuo, Fan, Yu, Sun, Changhong, Gu, Jin, Xi, Jianzhong Jeff
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105756/
https://www.ncbi.nlm.nih.gov/pubmed/24962367
http://dx.doi.org/10.1261/rna.044651.114