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A homolog of lariat-debranching enzyme modulates turnover of branched RNA

Turnover of the branched RNA intermediates and products of pre-mRNA splicing is mediated by the lariat-debranching enzyme Dbr1. We characterized a homolog of Dbr1 from Saccharomyces cerevisiae, Drn1/Ygr093w, that has a pseudo-metallophosphodiesterase domain with primary sequence homology to Dbr1 but...

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Detalles Bibliográficos
Autores principales:	Garrey, Stephen M., Katolik, Adam, Prekeris, Mantas, Li, Xueni, York, Kerri, Bernards, Sarah, Fields, Stanley, Zhao, Rui, Damha, Masad J., Hesselberth, Jay R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2014
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105757/ https://www.ncbi.nlm.nih.gov/pubmed/24919400 http://dx.doi.org/10.1261/rna.044602.114

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