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No clinical benefit of gender-specific total knee arthroplasty: A systematic review and meta-analysis of 6 randomized controlled trials
BACKGROUND AND PURPOSE: There is no consensus regarding the clinical relevance of gender-specific prostheses in total knee arthroplasty (TKA). We summarize the current best evidence in a comparison of clinical and radiographic outcomes between gender-specific prostheses and standard unisex prostheses...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Informa Healthcare
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105774/ https://www.ncbi.nlm.nih.gov/pubmed/24954488 http://dx.doi.org/10.3109/17453674.2014.931194 |
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author | Cheng, Tao Zhu, Chen Wang, Jiaxing Cheng, Mengqi Peng, Xiaochun Wang, Qi Zhang, Xianlong |
author_facet | Cheng, Tao Zhu, Chen Wang, Jiaxing Cheng, Mengqi Peng, Xiaochun Wang, Qi Zhang, Xianlong |
author_sort | Cheng, Tao |
collection | PubMed |
description | BACKGROUND AND PURPOSE: There is no consensus regarding the clinical relevance of gender-specific prostheses in total knee arthroplasty (TKA). We summarize the current best evidence in a comparison of clinical and radiographic outcomes between gender-specific prostheses and standard unisex prostheses in female patients. METHODS: We used the PubMed, Embase, Cochrane, Science Citation Index, and Scopus databases. We included randomized controlled trials published up to January 2013 that compared gender-specific prostheses with standard unisex prostheses in female patients who underwent primary TKAs. RESULTS: 6 trials involving 423 patients with 846 knee joints met the inclusion criteria. No statistically significant differences were observed between the 2 designs regarding pain, range of motion (ROM), knee scores, satisfaction, preference, complications, and radiographic results. The gender-specific design (Gender Solutions; Zimmer Inc, Warsaw, Indiana) reduced the prevalence of overhang. However, it had less overall coverage of the femoral condyles compared to the unisex group. In fact, the femoral prosthesis in the standard unisex group matched better than that in the gender-specific group. INTERPRETATION: Gender-specific prostheses do not appear to confer any benefit in terms of clinician- and patient-reported outcomes for the female knee. |
format | Online Article Text |
id | pubmed-4105774 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Informa Healthcare |
record_format | MEDLINE/PubMed |
spelling | pubmed-41057742014-08-07 No clinical benefit of gender-specific total knee arthroplasty: A systematic review and meta-analysis of 6 randomized controlled trials Cheng, Tao Zhu, Chen Wang, Jiaxing Cheng, Mengqi Peng, Xiaochun Wang, Qi Zhang, Xianlong Acta Orthop Knee BACKGROUND AND PURPOSE: There is no consensus regarding the clinical relevance of gender-specific prostheses in total knee arthroplasty (TKA). We summarize the current best evidence in a comparison of clinical and radiographic outcomes between gender-specific prostheses and standard unisex prostheses in female patients. METHODS: We used the PubMed, Embase, Cochrane, Science Citation Index, and Scopus databases. We included randomized controlled trials published up to January 2013 that compared gender-specific prostheses with standard unisex prostheses in female patients who underwent primary TKAs. RESULTS: 6 trials involving 423 patients with 846 knee joints met the inclusion criteria. No statistically significant differences were observed between the 2 designs regarding pain, range of motion (ROM), knee scores, satisfaction, preference, complications, and radiographic results. The gender-specific design (Gender Solutions; Zimmer Inc, Warsaw, Indiana) reduced the prevalence of overhang. However, it had less overall coverage of the femoral condyles compared to the unisex group. In fact, the femoral prosthesis in the standard unisex group matched better than that in the gender-specific group. INTERPRETATION: Gender-specific prostheses do not appear to confer any benefit in terms of clinician- and patient-reported outcomes for the female knee. Informa Healthcare 2014-08 2014-07-14 /pmc/articles/PMC4105774/ /pubmed/24954488 http://dx.doi.org/10.3109/17453674.2014.931194 Text en Copyright: © Nordic Orthopaedic Federation http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open-access article distributed under the terms of the CC-BY-NC-ND 3.0 License which permits users to download and share the article for non-commercial purposes, so long as the article is reproduced in the whole without changes, and provided the original source is credited. |
spellingShingle | Knee Cheng, Tao Zhu, Chen Wang, Jiaxing Cheng, Mengqi Peng, Xiaochun Wang, Qi Zhang, Xianlong No clinical benefit of gender-specific total knee arthroplasty: A systematic review and meta-analysis of 6 randomized controlled trials |
title | No clinical benefit of gender-specific total knee arthroplasty: A systematic review and meta-analysis of 6 randomized controlled trials |
title_full | No clinical benefit of gender-specific total knee arthroplasty: A systematic review and meta-analysis of 6 randomized controlled trials |
title_fullStr | No clinical benefit of gender-specific total knee arthroplasty: A systematic review and meta-analysis of 6 randomized controlled trials |
title_full_unstemmed | No clinical benefit of gender-specific total knee arthroplasty: A systematic review and meta-analysis of 6 randomized controlled trials |
title_short | No clinical benefit of gender-specific total knee arthroplasty: A systematic review and meta-analysis of 6 randomized controlled trials |
title_sort | no clinical benefit of gender-specific total knee arthroplasty: a systematic review and meta-analysis of 6 randomized controlled trials |
topic | Knee |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105774/ https://www.ncbi.nlm.nih.gov/pubmed/24954488 http://dx.doi.org/10.3109/17453674.2014.931194 |
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