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Analyzing networks of phenotypes in complex diseases: methodology and applications in COPD
BACKGROUND: The investigation of complex disease heterogeneity has been challenging. Here, we introduce a network-based approach, using partial correlations, that analyzes the relationships among multiple disease-related phenotypes. RESULTS: We applied this method to two large, well-characterized st...
Autores principales: | Chu, Jen-hwa, Hersh, Craig P, Castaldi, Peter J, Cho, Michael H, Raby, Benjamin A, Laird, Nan, Bowler, Russell, Rennard, Stephen, Loscalzo, Joseph, Quackenbush, John, Silverman, Edwin K |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105829/ https://www.ncbi.nlm.nih.gov/pubmed/24964944 http://dx.doi.org/10.1186/1752-0509-8-78 |
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