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Placental gene-expression profiles of intrahepatic cholestasis of pregnancy reveal involvement of multiple molecular pathways in blood vessel formation and inflammation

BACKGROUND: Intrahepatic cholestasis of pregnancy (ICP) is a pregnancy-associated liver disease with potentially deleterious consequences for the fetus, particularly when maternal serum bile-acid concentration >40 μM. However, the etiology and pathogenesis of ICP remain elusive. To reveal the und...

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Detalles Bibliográficos
Autores principales: Du, QiaoLing, Pan, YouDong, Zhang, YouHua, Zhang, HaiLong, Zheng, YaJuan, Lu, Ling, Wang, JunLei, Duan, Tao, Chen, JianFeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105836/
https://www.ncbi.nlm.nih.gov/pubmed/25001852
http://dx.doi.org/10.1186/1755-8794-7-42