The indoleamine 2,3-dioxygenase pathway controls complement-dependent enhancement of chemo-radiation therapy against murine glioblastoma

BACKGROUND: Indoleamine 2,3-dioxygenase (IDO) is an enzyme with immune-suppressive properties that is commonly exploited by tumors to evade immune destruction. Anti-tumor T cell responses can be initiated in solid tumors, but are immediately suppressed by compensatory upregulation of immunological c...

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Detalles Bibliográficos
Autores principales: Li, Minghui, Bolduc, Aaron R, Hoda, Md Nasrul, Gamble, Denise N, Dolisca, Sarah-Bianca, Bolduc, Anna K, Hoang, Kelly, Ashley, Claire, McCall, David, Rojiani, Amyn M, Maria, Bernard L, Rixe, Olivier, MacDonald, Tobey J, Heeger, Peter S, Mellor, Andrew L, Munn, David H, Johnson, Theodore S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105871/
https://www.ncbi.nlm.nih.gov/pubmed/25054064
http://dx.doi.org/10.1186/2051-1426-2-21

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