How much do we know about the coupling of G-proteins to serotonin receptors?

Serotonin receptors are G-protein-coupled receptors (GPCRs) involved in a variety of psychiatric disorders. G-proteins, heterotrimeric complexes that couple to multiple receptors, are activated when their receptor is bound by the appropriate ligand. Activation triggers a cascade of further signallin...

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Detalles Bibliográficos
Autores principales: Giulietti, Matteo, Vivenzio, Viviana, Piva, Francesco, Principato, Giovanni, Bellantuono, Cesario, Nardi, Bernardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105882/
https://www.ncbi.nlm.nih.gov/pubmed/25011628
http://dx.doi.org/10.1186/s13041-014-0049-y

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