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Lack of group X secreted phospholipase A(2) increases survival following pandemic H1N1 influenza infection
The role of Group X secreted phospholipase A(2) (GX-sPLA(2)) during influenza infection has not been previously investigated. We examined the role of GX-sPLA(2) during H1N1 pandemic influenza infection in a GX-sPLA(2) gene targeted mouse (GX(−/−)) model and found that survival after infection was si...
Autores principales: | Kelvin, Alyson A., Degousee, Norbert, Banner, David, Stefanski, Eva, Leόn, Alberto J., Angoulvant, Denis, Paquette, Stéphane G., Huang, Stephen S.H., Danesh, Ali, Robbins, Clinton S., Noyan, Hossein, Husain, Mansoor, Lambeau, Gerard, Gelb, Michael, Kelvin, David J., Rubin, Barry B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Authors. Published by Elsevier Inc.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106042/ https://www.ncbi.nlm.nih.gov/pubmed/24725934 http://dx.doi.org/10.1016/j.virol.2014.01.030 |
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