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The Mathematics of a Successful Deconvolution: A Quantitative Assessment of Mixture-Based Combinatorial Libraries Screened Against Two Formylpeptide Receptors

In the past 20 years, synthetic combinatorial methods have fundamentally advanced the ability to synthesize and screen large numbers of compounds for drug discovery and basic research. Mixture-based libraries and positional scanning deconvolution combine two approaches for the rapid identification o...

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Detalles Bibliográficos
Autores principales:	Santos, Radleigh G., Appel, Jon R., Giulianotti, Marc A., Edwards, Bruce S., Sklar, Larry A., Houghten, Richard A., Pinilla, Clemencia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106117/ https://www.ncbi.nlm.nih.gov/pubmed/23722730 http://dx.doi.org/10.3390/molecules18066408

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