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Analysis of the Retromer complex-WASH complex interaction illuminates new avenues to explore in Parkinson disease

The retromer complex mediates endosomal protein sorting by concentrating membrane proteins (cargo) into nascent tubules formed through the action of sorting nexin (SNX) proteins. The WASH complex is recruited to endosomes by binding to the VPS35 subunit of retromer and facilitates cargo protein sort...

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Detalles Bibliográficos
Autores principales:	Seaman, Matthew NJ, Freeman, Caroline L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Landes Bioscience 2014
Materias:	Article Addendum
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106150/ https://www.ncbi.nlm.nih.gov/pubmed/25067992 http://dx.doi.org/10.4161/cib.29483

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