Tertiary lymphoid structures in human lung cancers, a new driver of antitumor immune responses

T-cell infiltrates are robust prognostic biomarkers in the majority of human cancers. However, the mechanisms that shape a protective T-cell response remain unclear. Our recent study implicates tertiary lymphoid structures in the shaping of an efficient and beneficial immune response in lung cancer...

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Autores principales: Goc, Jérémy, Fridman, Wolf-Herman, Hammond, Scott A, Sautès-Fridman, Catherine, Dieu-Nosjean, Marie-Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106161/
https://www.ncbi.nlm.nih.gov/pubmed/25083325
http://dx.doi.org/10.4161/onci.28976
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author Goc, Jérémy
Fridman, Wolf-Herman
Hammond, Scott A
Sautès-Fridman, Catherine
Dieu-Nosjean, Marie-Caroline
author_facet Goc, Jérémy
Fridman, Wolf-Herman
Hammond, Scott A
Sautès-Fridman, Catherine
Dieu-Nosjean, Marie-Caroline
author_sort Goc, Jérémy
collection PubMed
description T-cell infiltrates are robust prognostic biomarkers in the majority of human cancers. However, the mechanisms that shape a protective T-cell response remain unclear. Our recent study implicates tertiary lymphoid structures in the shaping of an efficient and beneficial immune response in lung cancer patients.
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spelling pubmed-41061612014-07-31 Tertiary lymphoid structures in human lung cancers, a new driver of antitumor immune responses Goc, Jérémy Fridman, Wolf-Herman Hammond, Scott A Sautès-Fridman, Catherine Dieu-Nosjean, Marie-Caroline Oncoimmunology Author's View T-cell infiltrates are robust prognostic biomarkers in the majority of human cancers. However, the mechanisms that shape a protective T-cell response remain unclear. Our recent study implicates tertiary lymphoid structures in the shaping of an efficient and beneficial immune response in lung cancer patients. Landes Bioscience 2014-05-29 /pmc/articles/PMC4106161/ /pubmed/25083325 http://dx.doi.org/10.4161/onci.28976 Text en Copyright © 2014 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Goc, Jérémy
Fridman, Wolf-Herman
Hammond, Scott A
Sautès-Fridman, Catherine
Dieu-Nosjean, Marie-Caroline
Tertiary lymphoid structures in human lung cancers, a new driver of antitumor immune responses
title Tertiary lymphoid structures in human lung cancers, a new driver of antitumor immune responses
title_full Tertiary lymphoid structures in human lung cancers, a new driver of antitumor immune responses
title_fullStr Tertiary lymphoid structures in human lung cancers, a new driver of antitumor immune responses
title_full_unstemmed Tertiary lymphoid structures in human lung cancers, a new driver of antitumor immune responses
title_short Tertiary lymphoid structures in human lung cancers, a new driver of antitumor immune responses
title_sort tertiary lymphoid structures in human lung cancers, a new driver of antitumor immune responses
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106161/
https://www.ncbi.nlm.nih.gov/pubmed/25083325
http://dx.doi.org/10.4161/onci.28976
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