Tertiary lymphoid tissue: A gateway for T cells in the tumor microenvironment

Tumor-infiltrating lymphocytes influence colorectal cancer progression. We have recently documented that tertiary lymphoid tissue in the colorectal cancer microenvironment orchestrates lymphocyte infiltration and that tertiary lymphoid tissue and lymphocytes cooperate in a coordinated antitumor immu...

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Detalles Bibliográficos
Autores principales: Di Caro, Giuseppe, Marchesi, Federica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106162/
https://www.ncbi.nlm.nih.gov/pubmed/25083321
http://dx.doi.org/10.4161/onci.28850
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author Di Caro, Giuseppe
Marchesi, Federica
author_facet Di Caro, Giuseppe
Marchesi, Federica
author_sort Di Caro, Giuseppe
collection PubMed
description Tumor-infiltrating lymphocytes influence colorectal cancer progression. We have recently documented that tertiary lymphoid tissue in the colorectal cancer microenvironment orchestrates lymphocyte infiltration and that tertiary lymphoid tissue and lymphocytes cooperate in a coordinated antitumor immune response to improve patient outcome. Thus, tertiary lymphoid tissue represents a potential target in the design of tailored immune-based therapeutic approaches.
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spelling pubmed-41061622014-07-31 Tertiary lymphoid tissue: A gateway for T cells in the tumor microenvironment Di Caro, Giuseppe Marchesi, Federica Oncoimmunology Author's View Tumor-infiltrating lymphocytes influence colorectal cancer progression. We have recently documented that tertiary lymphoid tissue in the colorectal cancer microenvironment orchestrates lymphocyte infiltration and that tertiary lymphoid tissue and lymphocytes cooperate in a coordinated antitumor immune response to improve patient outcome. Thus, tertiary lymphoid tissue represents a potential target in the design of tailored immune-based therapeutic approaches. Landes Bioscience 2014-05-15 /pmc/articles/PMC4106162/ /pubmed/25083321 http://dx.doi.org/10.4161/onci.28850 Text en Copyright © 2014 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Di Caro, Giuseppe
Marchesi, Federica
Tertiary lymphoid tissue: A gateway for T cells in the tumor microenvironment
title Tertiary lymphoid tissue: A gateway for T cells in the tumor microenvironment
title_full Tertiary lymphoid tissue: A gateway for T cells in the tumor microenvironment
title_fullStr Tertiary lymphoid tissue: A gateway for T cells in the tumor microenvironment
title_full_unstemmed Tertiary lymphoid tissue: A gateway for T cells in the tumor microenvironment
title_short Tertiary lymphoid tissue: A gateway for T cells in the tumor microenvironment
title_sort tertiary lymphoid tissue: a gateway for t cells in the tumor microenvironment
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106162/
https://www.ncbi.nlm.nih.gov/pubmed/25083321
http://dx.doi.org/10.4161/onci.28850
work_keys_str_mv AT dicarogiuseppe tertiarylymphoidtissueagatewayfortcellsinthetumormicroenvironment
AT marchesifederica tertiarylymphoidtissueagatewayfortcellsinthetumormicroenvironment

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