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The Oligomeric States of the Purified Sigma-1 Receptor Are Stabilized by Ligands
Sigma-1 receptor (S1R) is a mammalian member of the ERG2 and sigma-1 receptor-like protein family (pfam04622). It has been implicated in drug addiction and many human neurological disorders, including Alzheimer and Parkinson diseases and amyotrophic lateral sclerosis. A broad range of synthetic smal...
Autores principales: | Gromek, Katarzyna A., Suchy, Fabian P., Meddaugh, Hannah R., Wrobel, Russell L., LaPointe, Loren M., Chu, Uyen B., Primm, John G., Ruoho, Arnold E., Senes, Alessandro, Fox, Brian G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106346/ https://www.ncbi.nlm.nih.gov/pubmed/24847081 http://dx.doi.org/10.1074/jbc.M113.537993 |
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