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The Oligomeric States of the Purified Sigma-1 Receptor Are Stabilized by Ligands

Sigma-1 receptor (S1R) is a mammalian member of the ERG2 and sigma-1 receptor-like protein family (pfam04622). It has been implicated in drug addiction and many human neurological disorders, including Alzheimer and Parkinson diseases and amyotrophic lateral sclerosis. A broad range of synthetic smal...

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Detalles Bibliográficos
Autores principales: Gromek, Katarzyna A., Suchy, Fabian P., Meddaugh, Hannah R., Wrobel, Russell L., LaPointe, Loren M., Chu, Uyen B., Primm, John G., Ruoho, Arnold E., Senes, Alessandro, Fox, Brian G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106346/
https://www.ncbi.nlm.nih.gov/pubmed/24847081
http://dx.doi.org/10.1074/jbc.M113.537993

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