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The Molecular Basis of Ligand Interaction at Free Fatty Acid Receptor 4 (FFA4/GPR120)

The long-chain fatty acid receptor FFA4 (previously GPR120) is receiving substantial interest as a novel target for the treatment of metabolic and inflammatory disease. This study examines for the first time the detailed mode of binding of both long-chain fatty acid and synthetic agonist ligands at...

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Detalles Bibliográficos
Autores principales:	Hudson, Brian D., Shimpukade, Bharat, Milligan, Graeme, Ulven, Trond
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2014
Materias:	Signal Transduction
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106347/ https://www.ncbi.nlm.nih.gov/pubmed/24860101 http://dx.doi.org/10.1074/jbc.M114.561449

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