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ARF: a versatile DNA damage response ally at the crossroads of development and tumorigenesis

Alternative reading frame (ARF) is a tumor suppressor protein that senses oncogenic and other stressogenic signals. It can trigger p53-dependent and -independent responses with cell cycle arrest and apoptosis induction being the most prominent ones. Other ARF activities, particularly p53-independent...

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Detalles Bibliográficos
Autores principales:	Kotsinas, Athanassios, Papanagnou, Panagiota, Evangelou, Konstantinos, Trigas, George C., Kostourou, Vassiliki, Townsend, Paul, Gorgoulis, Vassilis G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2014
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106421/ https://www.ncbi.nlm.nih.gov/pubmed/25101116 http://dx.doi.org/10.3389/fgene.2014.00236

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