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Areca Nut Components Affect COX-2, Cyclin B1/cdc25C and Keratin Expression, PGE2 Production in Keratinocyte Is Related to Reactive Oxygen Species, CYP1A1, Src, EGFR and Ras Signaling

AIMS: Chewing of betel quid (BQ) increases the risk of oral cancer and oral submucous fibrosis (OSF), possibly by BQ-induced toxicity and induction of inflammatory response in oral mucosa. METHODS: Primary gingival keratinocytes (GK cells) were exposed to areca nut (AN) components with/without inhib...

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Detalles Bibliográficos
Autores principales:	Chang, Mei-Chi, Chen, Yi-Jane, Chang, Hsiao-Hua, Chan, Chiu-Po, Yeh, Chien-Yang, Wang, Yin-Lin, Cheng, Ru-Hsiu, Hahn, Liang-Jiunn, Jeng, Jiiang-Huei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106785/ https://www.ncbi.nlm.nih.gov/pubmed/25051199 http://dx.doi.org/10.1371/journal.pone.0101959

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