Cargando…

RhoJ interacts with the GIT–PIX complex and regulates focal adhesion disassembly

RhoJ is a Rho GTPase expressed in endothelial cells and tumour cells, which regulates cell motility, invasion, endothelial tube formation and focal adhesion numbers. This study aimed to further delineate the molecular function of RhoJ. Using timelapse microscopy RhoJ was found to regulate focal adhe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wilson, Eleanor, Leszczynska, Katarzyna, Poulter, Natalie S., Edelmann, Francesca, Salisbury, Victoria A., Noy, Peter J., Bacon, Andrea, Rappoport, Joshua Z., Heath, John K., Bicknell, Roy, Heath, Victoria L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106786/ https://www.ncbi.nlm.nih.gov/pubmed/24928894 http://dx.doi.org/10.1242/jcs.140434

Ejemplares similares

Rho GTPase RhoJ is Associated with Gastric Cancer Progression and Metastasis
por: Kim, Chan, et al.
Publicado: (2016)

The Role of RhoJ in Endothelial Cell Biology and Tumor Pathology
por: Shi, Ting-Ting, et al.
Publicado: (2016)

Oncogenic Gαq activates RhoJ through PDZ-RhoGEF
por: Cervantes-Villagrana, Rodolfo Daniel, et al.
Publicado: (2023)

The RhoJ-BAD signaling network: An Achilles’ heel for BRAF mutant melanomas
por: Ruiz, Rolando, et al.
Publicado: (2017)

A functional antagonism between RhoJ and Cdc42 regulates fibronectin remodelling during angiogenesis
por: Sundararaman, Ananthalakshmy, et al.
Publicado: (2020)

GIT1 and βPIX Are Essential for GABA(A) Receptor Synaptic Stability and Inhibitory Neurotransmission
por: Smith, Katharine R., et al.
Publicado: (2014)

MKL1 Mediates TGF-β Induced RhoJ Transcription to Promote Breast Cancer Cell Migration and Invasion
por: Chen, Baoyu, et al.
Publicado: (2020)

RhoJ facilitates angiogenesis in glioblastoma via JNK/VEGFR2 mediated activation of PAK and ERK signaling pathways
por: Wang, Mei, et al.
Publicado: (2022)

The GIT–PIX complexes regulate the chemotactic response of rat basophilic leukaemia cells
por: Gavina, Manuela, et al.
Publicado: (2010)

Kinesin-1-dependent transport of the βPIX/GIT complex in neuronal cells
por: Shin, Eun-Young, et al.
Publicado: (2021)

Arhgef15 Promotes Retinal Angiogenesis by Mediating VEGF-Induced Cdc42 Activation and Potentiating RhoJ Inactivation in Endothelial Cells
por: Kusuhara, Sentaro, et al.
Publicado: (2012)

The small GTPase RhoG regulates microtubule-mediated focal adhesion disassembly
por: Zinn, Ashtyn, et al.
Publicado: (2019)

Photocycle of Cyanobacteriochrome TePixJ
por: Hardman, Samantha J. O., et al.
Publicado: (2020)

RHOJ controls EMT-associated resistance to chemotherapy
por: Debaugnies, Maud, et al.
Publicado: (2023)

A RAC/CDC-42–Independent GIT/PIX/PAK Signaling Pathway Mediates Cell Migration in C. elegans
por: Lucanic, Mark, et al.
Publicado: (2008)

Paxillin phosphorylation at Ser273 localizes a GIT1–PIX–PAK complex and regulates adhesion and protrusion dynamics
por: Nayal, Anjana, et al.
Publicado: (2006)

The dPix-Git complex is essential to coordinate epithelial morphogenesis and regulate myosin during Drosophila egg chamber development
por: Dent, Lucas G., et al.
Publicado: (2019)

Integrin-mediated Signaling via Paxillin-GIT1-PIX Promotes Localized Rac Activation at the Leading Edge and Cell Migration
por: Li, Youjun, et al.
Publicado: (2020)

Construction of a synthetic methodology-based library and its application in identifying a GIT/PIX protein–protein interaction inhibitor
por: Gu, Jing, et al.
Publicado: (2022)

Ras homolog family member J (RHOJ): a key regulator of chemoresistance associated with epithelial-mesenchymal transition
por: Liu, Sijia, et al.
Publicado: (2023)

Version control with Git and GitHub
por: Magana, Alex, et al.
Publicado: (2018)

Practical Git: Confident Git Through Practice
por: Abildskov, Johan
Publicado: (2020)

Targeting the RhoGEF βPIX/COOL-1 in Glioblastoma: Proof of Concept Studies
por: Connor, Kate, et al.
Publicado: (2020)

Elucidating the Associated Biological Function and Clinical Significance of RHOJ Expression in Urothelial Carcinoma
por: Lu, Xin-Jie, et al.
Publicado: (2023)

Pro Git
por: Chacon, Scott, et al.
Publicado: (2014)

Professional Git
por: Laster, Brent
Publicado: (2016)

Git for humans
por: Demaree, David
Publicado: (2016)

Pro Git
por: Chacon, Scott
Publicado: (2009)

Pro Git
por: Chacon, Scott
Publicado: (2009)

Git in Practice
por: McQuaid, Mike
Publicado: (2014)

A Quick Introduction to Version Control with Git and GitHub
por: Blischak, John D., et al.
Publicado: (2016)

Ten Simple Rules for Taking Advantage of Git and GitHub
por: Perez-Riverol, Yasset, et al.
Publicado: (2016)

The Rho-GEF PIX-1 directs assembly or stability of lateral attachment structures between muscle cells
por: Moody, Jasmine C., et al.
Publicado: (2020)

Correction: Ten Simple Rules for Taking Advantage of Git and GitHub
Publicado: (2019)

biogitflow: development workflow protocols for bioinformatics pipelines with git and GitLab
por: Kamoun, Choumouss, et al.
Publicado: (2021)

Identification of MYO18A as a Novel Interacting Partner of the PAK2/βPIX/GIT1 Complex and Its Potential Function in Modulating Epithelial Cell Migration
por: Hsu, Rae-Mann, et al.
Publicado: (2010)

The VeloPix ASIC
por: Poikela, Tuomas, et al.
Publicado: (2017)

Inside PixInsight
por: Keller, Warren A
Publicado: (2018)

Inside PixInsight
por: Keller, Warren A
Publicado: (2016)

Symposium on BIO-PIXE
Publicado: (1992)

Cannot write session to /tmp/vufind_sessions/sess_0ctm81k6f29g1jh3bumu58bvbd