Intracellular Clusterin Interacts with Brain Isoforms of the Bridging Integrator 1 and with the Microtubule-Associated Protein Tau in Alzheimer's Disease

Sporadic or late-onset Alzheimer's disease (AD) is expected to affect 50% of individuals reaching 85 years of age. The most significant genetic risk factor for late-onset AD is the e4 allele of APOE gene encoding apolipoprotein E, a lipid carrier shown to modulate brain amyloid burden. Recent g...

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Detalles Bibliográficos
Autores principales: Zhou, Yuan, Hayashi, Ikuo, Wong, Jacky, Tugusheva, Katherine, Renger, John J., Zerbinatti, Celina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106906/
https://www.ncbi.nlm.nih.gov/pubmed/25051234
http://dx.doi.org/10.1371/journal.pone.0103187

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