Inherited variation in the PARP1 gene and survival from melanoma

We report the association of an inherited variant located upstream of the poly(adenosine diphosphate-ribose) polymerase 1 (PARP1) gene (rs2249844), with survival in 11 BioGenoMEL melanoma cohorts. The gene encodes a protein involved in a number of cellular processes including single-strand DNA repai...

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Detalles Bibliográficos
Autores principales: Davies, John R, Jewell, Rosalyn, Affleck, Paul, Anic, Gabriella M, Randerson-Moor, Juliette, Ozola, Aija, Egan, Kathleen M, Elliott, Faye, García-Casado, Zaida, Hansson, Johan, Harland, Mark, Höiom, Veronica, Jian, Guan, Jönsson, Göran, Kumar, Rajiv, Nagore, Eduardo, Wendt, Judith, Olsson, Håkan, Park, Jong Y, Patel, Poulam, Pjanova, Dace, Puig, Susana, Schadendorf, Dirk, Sivaramakrishna Rachakonda, P, Snowden, Helen, Stratigos, Alexander J, Bafaloukos, Dimitrios, Ogbah, Zighereda, Sucker, Antje, Van den Oord, Joost J, Van Doorn, Remco, Walker, Christy, Okamoto, Ichiro, Wolter, Pascal, Barrett, Jennifer H, Timothy Bishop, D, Newton-Bishop, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Epidemiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106984/
https://www.ncbi.nlm.nih.gov/pubmed/24535833
http://dx.doi.org/10.1002/ijc.28796

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