Effective inhibition of colon cancer cell growth with MgAl-layered double hydroxide (LDH) loaded 5-FU and PI3K/mTOR dual inhibitor BEZ-235 through apoptotic pathways

Colon cancer is the third most common cancer and the third largest cause of cancer-related death. Fluorouracil (5-FU) is the front-line chemotherapeutic agent for colon cancer. However, its response rate is less than 60%, even in combination with other chemotherapeutic agents. The side effects of 5-...

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Detalles Bibliográficos
Autores principales: Chen, Jiezhong, Shao, Renfu, Li, Li, Xu, Zhi Ping, Gu, Wenyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107171/
https://www.ncbi.nlm.nih.gov/pubmed/25075187
http://dx.doi.org/10.2147/IJN.S61633

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107171/
https://www.ncbi.nlm.nih.gov/pubmed/25075187
http://dx.doi.org/10.2147/IJN.S61633

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