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Two Cases of Infantile Intra-abdominal Inflammatory Myofibroblastic Tumor

Inflammatory myofibroblastic tumor (IMT) is rare mesenchymal solid tumor that consists of proliferating myofibroblasts with an inflammatory infiltrate background. It has a very low prevalence in infants and occurs mainly in children and young adults. IMT are mainly located in the thoracic cavity, bu...

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Autores principales: Kim, Soo-Hong, Cho, Yong Hoon, Kim, Hae Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Pediatric Gastroenterology, Hepatology and Nutrition 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107219/
https://www.ncbi.nlm.nih.gov/pubmed/25061588
http://dx.doi.org/10.5223/pghn.2014.17.2.116
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author Kim, Soo-Hong
Cho, Yong Hoon
Kim, Hae Young
author_facet Kim, Soo-Hong
Cho, Yong Hoon
Kim, Hae Young
author_sort Kim, Soo-Hong
collection PubMed
description Inflammatory myofibroblastic tumor (IMT) is rare mesenchymal solid tumor that consists of proliferating myofibroblasts with an inflammatory infiltrate background. It has a very low prevalence in infants and occurs mainly in children and young adults. IMT are mainly located in the thoracic cavity, but intra-abdominal lesions are rare. IMT can exhibit locally aggressive neoplastic processes and metastases similar to malignancies, so, have clinical importance. Herein, we describe two infantile intra-abdominal IMT cases presenting with incidentally found palpable abdominal mass. A 4-month-old male infant had IMT at the ileal mesentery and a 5-month-old male infant had IMT at liver. Both cases were successfully treated by complete surgical resection without complication or recurrence. Considering the biological behavior of the intermediate type of neoplasm in IMT, we expect good survivals when achieving appropriate surgical resection without adjuvant therapy in infantile intra-abdominal IMT.
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spelling pubmed-41072192014-07-24 Two Cases of Infantile Intra-abdominal Inflammatory Myofibroblastic Tumor Kim, Soo-Hong Cho, Yong Hoon Kim, Hae Young Pediatr Gastroenterol Hepatol Nutr Case Report Inflammatory myofibroblastic tumor (IMT) is rare mesenchymal solid tumor that consists of proliferating myofibroblasts with an inflammatory infiltrate background. It has a very low prevalence in infants and occurs mainly in children and young adults. IMT are mainly located in the thoracic cavity, but intra-abdominal lesions are rare. IMT can exhibit locally aggressive neoplastic processes and metastases similar to malignancies, so, have clinical importance. Herein, we describe two infantile intra-abdominal IMT cases presenting with incidentally found palpable abdominal mass. A 4-month-old male infant had IMT at the ileal mesentery and a 5-month-old male infant had IMT at liver. Both cases were successfully treated by complete surgical resection without complication or recurrence. Considering the biological behavior of the intermediate type of neoplasm in IMT, we expect good survivals when achieving appropriate surgical resection without adjuvant therapy in infantile intra-abdominal IMT. The Korean Society of Pediatric Gastroenterology, Hepatology and Nutrition 2014-06 2014-06-30 /pmc/articles/PMC4107219/ /pubmed/25061588 http://dx.doi.org/10.5223/pghn.2014.17.2.116 Text en Copyright © 2014 by The Korean Society of Pediatric Gastroenterology, Hepatology and Nutrition http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Kim, Soo-Hong
Cho, Yong Hoon
Kim, Hae Young
Two Cases of Infantile Intra-abdominal Inflammatory Myofibroblastic Tumor
title Two Cases of Infantile Intra-abdominal Inflammatory Myofibroblastic Tumor
title_full Two Cases of Infantile Intra-abdominal Inflammatory Myofibroblastic Tumor
title_fullStr Two Cases of Infantile Intra-abdominal Inflammatory Myofibroblastic Tumor
title_full_unstemmed Two Cases of Infantile Intra-abdominal Inflammatory Myofibroblastic Tumor
title_short Two Cases of Infantile Intra-abdominal Inflammatory Myofibroblastic Tumor
title_sort two cases of infantile intra-abdominal inflammatory myofibroblastic tumor
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107219/
https://www.ncbi.nlm.nih.gov/pubmed/25061588
http://dx.doi.org/10.5223/pghn.2014.17.2.116
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