Everything you need to know about distal renal tubular acidosis in autoimmune disease

Renal acid–base homeostasis is a complex process, effectuated by bicarbonate reabsorption and acid secretion. Impairment of urinary acidification is called renal tubular acidosis (RTA). Distal renal tubular acidosis (dRTA) is the most common form of the RTA syndromes. Multiple pathophysiologic mecha...

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Detalles Bibliográficos
Autores principales: Both, Tim, Zietse, Robert, Hoorn, Ewout J., van Hagen, P. Martin, Dalm, Virgil A. S. H., van Laar, Jan A. M., van Daele, Paul L. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107275/
https://www.ncbi.nlm.nih.gov/pubmed/24682397
http://dx.doi.org/10.1007/s00296-014-2993-3
Descripción
Sumario:Renal acid–base homeostasis is a complex process, effectuated by bicarbonate reabsorption and acid secretion. Impairment of urinary acidification is called renal tubular acidosis (RTA). Distal renal tubular acidosis (dRTA) is the most common form of the RTA syndromes. Multiple pathophysiologic mechanisms, each associated with various etiologies, can lead to dRTA. The most important consequence of dRTA is (recurrent) nephrolithiasis. The diagnosis is based on a urinary acidification test. Potassium citrate is the treatment of choice.

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