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Everything you need to know about distal renal tubular acidosis in autoimmune disease
Renal acid–base homeostasis is a complex process, effectuated by bicarbonate reabsorption and acid secretion. Impairment of urinary acidification is called renal tubular acidosis (RTA). Distal renal tubular acidosis (dRTA) is the most common form of the RTA syndromes. Multiple pathophysiologic mecha...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107275/ https://www.ncbi.nlm.nih.gov/pubmed/24682397 http://dx.doi.org/10.1007/s00296-014-2993-3 |
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author | Both, Tim Zietse, Robert Hoorn, Ewout J. van Hagen, P. Martin Dalm, Virgil A. S. H. van Laar, Jan A. M. van Daele, Paul L. A. |
author_facet | Both, Tim Zietse, Robert Hoorn, Ewout J. van Hagen, P. Martin Dalm, Virgil A. S. H. van Laar, Jan A. M. van Daele, Paul L. A. |
author_sort | Both, Tim |
collection | PubMed |
description | Renal acid–base homeostasis is a complex process, effectuated by bicarbonate reabsorption and acid secretion. Impairment of urinary acidification is called renal tubular acidosis (RTA). Distal renal tubular acidosis (dRTA) is the most common form of the RTA syndromes. Multiple pathophysiologic mechanisms, each associated with various etiologies, can lead to dRTA. The most important consequence of dRTA is (recurrent) nephrolithiasis. The diagnosis is based on a urinary acidification test. Potassium citrate is the treatment of choice. |
format | Online Article Text |
id | pubmed-4107275 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-41072752014-08-08 Everything you need to know about distal renal tubular acidosis in autoimmune disease Both, Tim Zietse, Robert Hoorn, Ewout J. van Hagen, P. Martin Dalm, Virgil A. S. H. van Laar, Jan A. M. van Daele, Paul L. A. Rheumatol Int Review Article Renal acid–base homeostasis is a complex process, effectuated by bicarbonate reabsorption and acid secretion. Impairment of urinary acidification is called renal tubular acidosis (RTA). Distal renal tubular acidosis (dRTA) is the most common form of the RTA syndromes. Multiple pathophysiologic mechanisms, each associated with various etiologies, can lead to dRTA. The most important consequence of dRTA is (recurrent) nephrolithiasis. The diagnosis is based on a urinary acidification test. Potassium citrate is the treatment of choice. Springer Berlin Heidelberg 2014-03-29 2014 /pmc/articles/PMC4107275/ /pubmed/24682397 http://dx.doi.org/10.1007/s00296-014-2993-3 Text en © The Author(s) 2014 https://creativecommons.org/licenses/by/4.0/ Open AccessThis article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited. |
spellingShingle | Review Article Both, Tim Zietse, Robert Hoorn, Ewout J. van Hagen, P. Martin Dalm, Virgil A. S. H. van Laar, Jan A. M. van Daele, Paul L. A. Everything you need to know about distal renal tubular acidosis in autoimmune disease |
title | Everything you need to know about distal renal tubular acidosis in autoimmune disease |
title_full | Everything you need to know about distal renal tubular acidosis in autoimmune disease |
title_fullStr | Everything you need to know about distal renal tubular acidosis in autoimmune disease |
title_full_unstemmed | Everything you need to know about distal renal tubular acidosis in autoimmune disease |
title_short | Everything you need to know about distal renal tubular acidosis in autoimmune disease |
title_sort | everything you need to know about distal renal tubular acidosis in autoimmune disease |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107275/ https://www.ncbi.nlm.nih.gov/pubmed/24682397 http://dx.doi.org/10.1007/s00296-014-2993-3 |
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