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Coordinated DNA dynamics during the human telomerase catalytic cycle

The human telomerase reverse transcriptase (hTERT) utilizes a template within the integral RNA subunit (hTR) to direct extension of telomeres. Telomerase exhibits repeat addition processivity (RAP) and must therefore translocate the nascent DNA product into a new RNA:DNA hybrid register to prime eac...

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Detalles Bibliográficos
Autores principales:	Parks, Joseph W., Stone, Michael D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107311/ https://www.ncbi.nlm.nih.gov/pubmed/24923681 http://dx.doi.org/10.1038/ncomms5146

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