The fidelity of the ligation step determines how ends are resolved during Nonhomologous end joining

Nonhomologous end joining (NHEJ) can effectively resolve chromosome breaks despite diverse end structures, but it is unclear how the steps employed for resolution are determined. We sought to address this question by analyzing cellular NHEJ of ends with systematically mispaired and damaged termini....

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Detalles Bibliográficos
Autores principales: Waters, Crystal A., Strande, Natasha T., Pryor, John M., Strom, Christina, Mieczkowski, Piotr, Burkhalter, Martin D., Oh, Sehyun, Qaqish, Bahjat F., Moore, Dominic T., Hendrickson, Eric A., Ramsden, Dale A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107315/
https://www.ncbi.nlm.nih.gov/pubmed/24989324
http://dx.doi.org/10.1038/ncomms5286

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