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GIV/Girdin is a central hub for pro-fibrogenic signalling networks during liver fibrosis
Progressive liver fibrosis is characterized by the deposition of collagen by activated hepatic stellate cells (HSCs). Activation of HSCs is a multiple receptor-driven process in which profibrotic signals are enhanced, and anti-fibrotic pathways are suppressed. Here we report the discovery of a novel...
Autores principales: | Lopez-Sanchez, Inmaculada, Dunkel, Ying, Roh, Yoon-Seok, Mittal, Yash, De Minicis, Samuele, Muranyi, Andrea, Singh, Shalini, Shanmugam, Kandavel, Aroonsakool, Nakon, Murray, Fiona, Ho, Samuel B., Seki, Ekihiro, Brenner, David A., Ghosh, Pradipta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107319/ https://www.ncbi.nlm.nih.gov/pubmed/25043713 http://dx.doi.org/10.1038/ncomms5451 |
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