Cargando…

Validation of a polygenic risk score for dementia in black and white individuals

OBJECTIVE: To determine whether a polygenic risk score for Alzheimer's disease (AD) predicts dementia probability and memory functioning in non-Hispanic black (NHB) and non-Hispanic white (NHW) participants from a sample not used in previous genome-wide association studies. METHODS: Non-Hispani...

Descripción completa

Detalles Bibliográficos
Autores principales:	Marden, Jessica R, Walter, Stefan, Tchetgen Tchetgen, Eric J, Kawachi, Ichiro, Glymour, M Maria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2014
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107377/ https://www.ncbi.nlm.nih.gov/pubmed/25328845 http://dx.doi.org/10.1002/brb3.248

Ejemplares similares

Performance of Polygenic Scores for Predicting Phobic Anxiety
por: Walter, Stefan, et al.
Publicado: (2013)

Genome-wide polygenic scoring for a 14-year long-term average depression phenotype
por: Chang, Shun-Chiao, et al.
Publicado: (2014)

The role of literacy in the association between educational attainment and depressive symptoms
por: Nguyen, Thu T., et al.
Publicado: (2017)

Changes in Depressive Symptoms and Incidence of First Stroke Among Middle-Aged and Older US Adults
por: Gilsanz, Paola, et al.
Publicado: (2015)

The Control Outcome Calibration Approach for Causal Inference With Unobserved Confounding
por: Tchetgen Tchetgen, Eric
Publicado: (2014)

Bachelors, Divorcees, and Widowers: Does Marriage Protect Men from Type 2 Diabetes?
por: Cornelis, Marilyn C., et al.
Publicado: (2014)

Identification and estimation of survivor average causal effects
por: Tchetgen, Eric J Tchetgen
Publicado: (2014)

Evaluation of Medication-mediated Effects in Pharmacoepidemiology
por: Tchetgen Tchetgen, Eric J., et al.
Publicado: (2017)

On varieties of doubly robust estimators under missingness not at random with a shadow variable
por: Miao, Wang, et al.
Publicado: (2016)

Universal Difference-in-Differences for Causal Inference in Epidemiology
por: Tchetgen Tchetgen, Eric J., et al.
Publicado: (2023)

University of Pennsylvania 11th annual conference on statistical issues in clinical trials: Estimands, missing data and sensitivity analysis (afternoon panel session)
por: Little, Roderick J, et al.
Publicado: (2019)

Double Negative Control Inference in Test-Negative Design Studies of Vaccine Effectiveness
por: Li, Kendrick Qijun, et al.
Publicado: (2023)

The Effect of Family Wealth on Physical Function Among Older Adults in Mpumalanga, South Africa: A Causal Network Analysis
por: Makofane, Keletso, et al.
Publicado: (2023)

The Association of Meningococcal Disease with Influenza in the United States, 1989–2009
por: Jacobs, Jessica Hartman, et al.
Publicado: (2014)

A generalized theory of separable effects in competing event settings
por: Stensrud, Mats J., et al.
Publicado: (2021)

Polygenic Risk Predicts Obesity in Both White and Black Young Adults
por: Domingue, Benjamin W., et al.
Publicado: (2014)

Tuberculosis Incidence and Risk Factors Among Human Immunodeficiency Virus (HIV)-Infected Adults Receiving Antiretroviral Therapy in a Large HIV Program in Nigeria
por: Chang, Charlotte A., et al.
Publicado: (2015)

Marginal structural model to evaluate the association between cumulative osteoporosis medication and infection using claims data
por: Xue, F., et al.
Publicado: (2017)

CD4 Recovery on Antiretroviral Therapy Is Associated With Decreased Progression to Liver Disease Among Hepatitis C Virus-Infected Injecting Drug Users
por: Anderson, Jeffrey P., et al.
Publicado: (2015)

Validation of a prostate cancer polygenic risk score
por: Black, Mary H., et al.
Publicado: (2020)

Effect of reductions in amyloid levels on cognitive change in randomized trials: instrumental variable meta-analysis
por: Ackley, Sarah F, et al.
Publicado: (2021)

Sibling validation of polygenic risk scores and complex trait prediction
por: Lello, Louis, et al.
Publicado: (2020)

Risk of dementia in APOE ε4 carriers is mitigated by a polygenic risk score
por: Ebenau, Jarith L., et al.
Publicado: (2021)

Individualized Polygenic Risk Score Identifies NASH in the Eastern Asia Region: A Derivation and Validation Study
por: Gao, Feng, et al.
Publicado: (2021)

Development and Validation of a Clinical Polygenic Risk Score to Predict Breast Cancer Risk
por: Hughes, Elisha, et al.
Publicado: (2020)

Identifying individuals with high risk of Alzheimer’s disease using polygenic risk scores
por: Leonenko, Ganna, et al.
Publicado: (2021)

Influence of polygenic risk scores for schizophrenia and resilience on the cognition of individuals at-risk for psychosis
por: He, Qin, et al.
Publicado: (2021)

Searching for Sharp Drops in the Incidence of Pandemic A/H1N1 Influenza by Single Year of Age
por: Jacobs, Jessica Hartman, et al.
Publicado: (2012)

Association Between Sleep Duration and Diabetes in Black and White Adults
por: Jackson, Chandra L., et al.
Publicado: (2013)

Polygenic risk scores for Alzheimer's disease are related to dementia risk in APOE ɛ4 negatives
por: Najar, Jenna, et al.
Publicado: (2021)

Validity and Prognostic Value of a Polygenic Risk Score for Parkinson’s Disease
por: Koch, Sebastian, et al.
Publicado: (2021)

Effect of APOE and a polygenic risk score on incident dementia and cognitive decline in a healthy older population
por: Riaz, Moeen, et al.
Publicado: (2021)

Polygenic transcriptome risk scores (PTRS) can improve portability of polygenic risk scores across ancestries
por: Liang, Yanyu, et al.
Publicado: (2022)

Polygenic Risk Scores and the Need for Pharmacotherapy in Neonatal Abstinence Syndrome
por: Bibi, Shawana, et al.
Publicado: (2023)

Polygenic risk score prediction of multiple sclerosis in individuals of South Asian ancestry
por: Breedon, Joshua R, et al.
Publicado: (2023)

PRSice: Polygenic Risk Score software
por: Euesden, Jack, et al.
Publicado: (2015)

Polygenic Risk Scores and Physical Activity
por: KUJALA, URHO M., et al.
Publicado: (2020)

Polygenic Risk Scores for Subtyping of Schizophrenia
por: Chen, Jingchun, et al.
Publicado: (2020)

Polygenic risk scores and rheumatic diseases
por: Brown, Matthew A., et al.
Publicado: (2021)

Polygenic Risk Score Prediction for Endometriosis
por: Kloeve-Mogensen, Kirstine, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_40qku9u86casoa7jkbps19vl7i