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Beneficial effects of environmental enrichment and food entrainment in the R6/2 mouse model of Huntington's disease
BACKGROUND: In addition to their cognitive and motor deficits, R6/2 mice show a progressive disintegration in circadian rhythms that mirrors the problems associated with sleep-wake disturbances experienced by patients with Huntington's disease (HD). It has been shown previously that motor and c...
Autores principales: | Skillings, Elizabeth A, Wood, Nigel I, Morton, A Jennifer |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107380/ https://www.ncbi.nlm.nih.gov/pubmed/25328844 http://dx.doi.org/10.1002/brb3.235 |
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