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Communicating with the non-dominant hemisphere: Implications for neurological rehabilitation☆
Aphasic syndromes usually result from injuries to the dominant hemisphere of the brain. Despite the fact that localization of language functions shows little interindividual variability, several brain areas are simultaneously activated when language tasks are undertaken. Mechanisms of language recov...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107603/ https://www.ncbi.nlm.nih.gov/pubmed/25206418 http://dx.doi.org/10.3969/j.issn.1673-5374.2013.13.009 |
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author | de Oliveira, Fabricio Ferreira Correia Marin, Sheilla de Medeiros Ferreira Bertolucci, Paulo Henrique |
author_facet | de Oliveira, Fabricio Ferreira Correia Marin, Sheilla de Medeiros Ferreira Bertolucci, Paulo Henrique |
author_sort | de Oliveira, Fabricio Ferreira |
collection | PubMed |
description | Aphasic syndromes usually result from injuries to the dominant hemisphere of the brain. Despite the fact that localization of language functions shows little interindividual variability, several brain areas are simultaneously activated when language tasks are undertaken. Mechanisms of language recovery after brain injury to the dominant hemisphere seem to be relatively stereotyped, including activations of perilesional areas in the acute phase and of homologues of language areas in the non-dominant hemisphere in the subacute phase, later returning to dominant hemisphere activation in the chronic phase. Plasticity mechanisms reopen the critical period of language development, more specifically in what leads to disinhibition of the non-dominant hemisphere when brain lesions affect the dominant hemisphere. The non-dominant hemisphere plays an important role during recovery from aphasia, but currently available rehabilitation therapies have shown limited results for efficient language improvement. Large-scale randomized controlled trials that evaluate well-defined interventions in patients with aphasia are needed for stimulation of neuroplasticity mechanisms that enhance the role of the non-dominant hemisphere for language recovery. Ineffective treatment approaches should be replaced by more promising ones and the latter should be evaluated for proper application. The data generated by such studies could substantiate evidence-based rehabilitation strategies for patients with aphasia. |
format | Online Article Text |
id | pubmed-4107603 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-41076032014-09-09 Communicating with the non-dominant hemisphere: Implications for neurological rehabilitation☆ de Oliveira, Fabricio Ferreira Correia Marin, Sheilla de Medeiros Ferreira Bertolucci, Paulo Henrique Neural Regen Res Review Article Aphasic syndromes usually result from injuries to the dominant hemisphere of the brain. Despite the fact that localization of language functions shows little interindividual variability, several brain areas are simultaneously activated when language tasks are undertaken. Mechanisms of language recovery after brain injury to the dominant hemisphere seem to be relatively stereotyped, including activations of perilesional areas in the acute phase and of homologues of language areas in the non-dominant hemisphere in the subacute phase, later returning to dominant hemisphere activation in the chronic phase. Plasticity mechanisms reopen the critical period of language development, more specifically in what leads to disinhibition of the non-dominant hemisphere when brain lesions affect the dominant hemisphere. The non-dominant hemisphere plays an important role during recovery from aphasia, but currently available rehabilitation therapies have shown limited results for efficient language improvement. Large-scale randomized controlled trials that evaluate well-defined interventions in patients with aphasia are needed for stimulation of neuroplasticity mechanisms that enhance the role of the non-dominant hemisphere for language recovery. Ineffective treatment approaches should be replaced by more promising ones and the latter should be evaluated for proper application. The data generated by such studies could substantiate evidence-based rehabilitation strategies for patients with aphasia. Medknow Publications & Media Pvt Ltd 2013-05-05 /pmc/articles/PMC4107603/ /pubmed/25206418 http://dx.doi.org/10.3969/j.issn.1673-5374.2013.13.009 Text en Copyright: © Neural Regeneration Research http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article de Oliveira, Fabricio Ferreira Correia Marin, Sheilla de Medeiros Ferreira Bertolucci, Paulo Henrique Communicating with the non-dominant hemisphere: Implications for neurological rehabilitation☆ |
title | Communicating with the non-dominant hemisphere: Implications for neurological rehabilitation☆ |
title_full | Communicating with the non-dominant hemisphere: Implications for neurological rehabilitation☆ |
title_fullStr | Communicating with the non-dominant hemisphere: Implications for neurological rehabilitation☆ |
title_full_unstemmed | Communicating with the non-dominant hemisphere: Implications for neurological rehabilitation☆ |
title_short | Communicating with the non-dominant hemisphere: Implications for neurological rehabilitation☆ |
title_sort | communicating with the non-dominant hemisphere: implications for neurological rehabilitation☆ |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107603/ https://www.ncbi.nlm.nih.gov/pubmed/25206418 http://dx.doi.org/10.3969/j.issn.1673-5374.2013.13.009 |
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