DNA damage-specific deubiquitination regulates Rad18 functions to suppress mutagenesis

Deoxyribonucleic acid (DNA) lesions encountered during replication are often bypassed using DNA damage tolerance (DDT) pathways to avoid prolonged fork stalling and allow for completion of DNA replication. Rad18 is a central E3 ubiquitin ligase in DDT, which exists in a monoubiquitinated (Rad18•Ub)...

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Detalles Bibliográficos
Autores principales: Zeman, Michelle K., Lin, Jia-Ren, Freire, Raimundo, Cimprich, Karlene A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107794/
https://www.ncbi.nlm.nih.gov/pubmed/25023518
http://dx.doi.org/10.1083/jcb.201311063

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107794/
https://www.ncbi.nlm.nih.gov/pubmed/25023518
http://dx.doi.org/10.1083/jcb.201311063

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