Phrenic Nerve Paralysis as the Initial Presentation in Pleural Sarcomatoid Mesothelioma

A 74-year-old man was referred to our hospital because of persistent cough. A chest radiograph revealed an elevation of the right diaphragm. Computed tomography (CT) images revealed a small nodule localized on the right mediastinum. Five months later, the nodule had grown and was diagnosed as malign...

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Autores principales: Makimoto, Go, Fujiwara, Keiichi, Fujimoto, Nobukazu, Yamadori, Ichiro, Sato, Toshio, Kishimoto, Takumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2014
Materias:
Published online: June, 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107822/
https://www.ncbi.nlm.nih.gov/pubmed/25076889
http://dx.doi.org/10.1159/000363760
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author Makimoto, Go
Fujiwara, Keiichi
Fujimoto, Nobukazu
Yamadori, Ichiro
Sato, Toshio
Kishimoto, Takumi
author_facet Makimoto, Go
Fujiwara, Keiichi
Fujimoto, Nobukazu
Yamadori, Ichiro
Sato, Toshio
Kishimoto, Takumi
author_sort Makimoto, Go
collection PubMed
description A 74-year-old man was referred to our hospital because of persistent cough. A chest radiograph revealed an elevation of the right diaphragm. Computed tomography (CT) images revealed a small nodule localized on the right mediastinum. Five months later, the nodule had grown and was diagnosed as malignant pleural mesothelioma (MPM) by a CT-guided needle biopsy. The patient underwent combined chemotherapy, but the disease progressed rapidly and he passed away. On autopsy, microscopic findings and immunohistological examinations supported the diagnosis of sarcomatoid mesothelioma. Therefore, we diagnosed this rare case as localized sarcomatoid MPM showing phrenic nerve paralysis as an initial presentation.
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spelling pubmed-41078222014-07-30 Phrenic Nerve Paralysis as the Initial Presentation in Pleural Sarcomatoid Mesothelioma Makimoto, Go Fujiwara, Keiichi Fujimoto, Nobukazu Yamadori, Ichiro Sato, Toshio Kishimoto, Takumi Case Rep Oncol Published online: June, 2014 A 74-year-old man was referred to our hospital because of persistent cough. A chest radiograph revealed an elevation of the right diaphragm. Computed tomography (CT) images revealed a small nodule localized on the right mediastinum. Five months later, the nodule had grown and was diagnosed as malignant pleural mesothelioma (MPM) by a CT-guided needle biopsy. The patient underwent combined chemotherapy, but the disease progressed rapidly and he passed away. On autopsy, microscopic findings and immunohistological examinations supported the diagnosis of sarcomatoid mesothelioma. Therefore, we diagnosed this rare case as localized sarcomatoid MPM showing phrenic nerve paralysis as an initial presentation. S. Karger AG 2014-06-14 /pmc/articles/PMC4107822/ /pubmed/25076889 http://dx.doi.org/10.1159/000363760 Text en Copyright © 2014 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article licensed under the terms of the Creative Commons Attribution-NonCommercial 3.0 Unported license (CC BY-NC) (www.karger.com/OA-license), applicable to the online version of the article only. Users may download, print and share this work on the Internet for noncommercial purposes only, provided the original work is properly cited, and a link to the original work on http://www.karger.com and the terms of this license are included in any shared versions.
spellingShingle Published online: June, 2014
Makimoto, Go
Fujiwara, Keiichi
Fujimoto, Nobukazu
Yamadori, Ichiro
Sato, Toshio
Kishimoto, Takumi
Phrenic Nerve Paralysis as the Initial Presentation in Pleural Sarcomatoid Mesothelioma
title Phrenic Nerve Paralysis as the Initial Presentation in Pleural Sarcomatoid Mesothelioma
title_full Phrenic Nerve Paralysis as the Initial Presentation in Pleural Sarcomatoid Mesothelioma
title_fullStr Phrenic Nerve Paralysis as the Initial Presentation in Pleural Sarcomatoid Mesothelioma
title_full_unstemmed Phrenic Nerve Paralysis as the Initial Presentation in Pleural Sarcomatoid Mesothelioma
title_short Phrenic Nerve Paralysis as the Initial Presentation in Pleural Sarcomatoid Mesothelioma
title_sort phrenic nerve paralysis as the initial presentation in pleural sarcomatoid mesothelioma
topic Published online: June, 2014
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107822/
https://www.ncbi.nlm.nih.gov/pubmed/25076889
http://dx.doi.org/10.1159/000363760
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