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Multiple chemical scaffolds inhibit a promising Leishmania drug target

The need for an effective oral therapy for leishmaniasis is addressed through the study of the target N-myristoyltransferase from Leishmania major.

Detalles Bibliográficos
Autor principal: Walkinshaw, Malcolm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107919/
https://www.ncbi.nlm.nih.gov/pubmed/25075340
http://dx.doi.org/10.1107/S2052252514014572
Descripción
Sumario:The need for an effective oral therapy for leishmaniasis is addressed through the study of the target N-myristoyltransferase from Leishmania major.