Structure and function study of the complex that synthesizes S-adenosylmethionine

S-Adenosylmethionine (SAMe) is the principal methyl donor of the cell and is synthesized via an ATP-driven process by methionine adenosyltransferase (MAT) enzymes. It is tightly linked with cell proliferation in liver and colon cancer. In humans, there are three genes, mat1A, mat2A and mat2B, which...

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Detalles Bibliográficos
Autores principales: Murray, Ben, Antonyuk, Svetlana V., Marina, Alberto, Van Liempd, Sebastiaan M., Lu, Shelly C., Mato, Jose M., Hasnain, S. Samar, Rojas, Adriana L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2014
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107924/
https://www.ncbi.nlm.nih.gov/pubmed/25075345
http://dx.doi.org/10.1107/S2052252514012585

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107924/
https://www.ncbi.nlm.nih.gov/pubmed/25075345
http://dx.doi.org/10.1107/S2052252514012585

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