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Pattern Recognition and Signaling Mechanisms of RIG-I and MDA5

Most organisms rely on innate immune receptors to recognize conserved molecular structures from invading microbes. Two essential innate immune receptors, RIG-I and MDA5, detect viral double-stranded RNA in the cytoplasm. The inflammatory response triggered by these RIG-I-like receptors (RLRs) is one...

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Detalles Bibliográficos
Autores principales:	Reikine, Stephanie, Nguyen, Jennifer B., Modis, Yorgo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2014
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107945/ https://www.ncbi.nlm.nih.gov/pubmed/25101084 http://dx.doi.org/10.3389/fimmu.2014.00342

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