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Nanotechnology in drug delivery: the need for more cell culture based studies in screening
Advances in biomedical science are leading to upsurge synthesis of nanodelivery systems for drug delivery. The systems were characterized by controlled, targeted and sustained drug delivery ability. Humans are the target of these systems, hence, animals whose systems resembles humans were used to pr...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108003/ https://www.ncbi.nlm.nih.gov/pubmed/25057288 http://dx.doi.org/10.1186/1752-153X-8-46 |
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author | Kura, Aminu Umar Fakurazi, Sharida Hussein, Mohd Zobir Arulselvan, Palanisamy |
author_facet | Kura, Aminu Umar Fakurazi, Sharida Hussein, Mohd Zobir Arulselvan, Palanisamy |
author_sort | Kura, Aminu Umar |
collection | PubMed |
description | Advances in biomedical science are leading to upsurge synthesis of nanodelivery systems for drug delivery. The systems were characterized by controlled, targeted and sustained drug delivery ability. Humans are the target of these systems, hence, animals whose systems resembles humans were used to predict outcome. Thus, increasing costs in money and time, plus ethical concerns over animal usage. However, with consideration and planning in experimental conditions, in vitro pharmacological studies of the nanodelivery can mimic the in vivo system. This can function as a simple method to investigate the effect of such materials without endangering animals especially at screening phase. |
format | Online Article Text |
id | pubmed-4108003 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-41080032014-07-24 Nanotechnology in drug delivery: the need for more cell culture based studies in screening Kura, Aminu Umar Fakurazi, Sharida Hussein, Mohd Zobir Arulselvan, Palanisamy Chem Cent J Mini Review Advances in biomedical science are leading to upsurge synthesis of nanodelivery systems for drug delivery. The systems were characterized by controlled, targeted and sustained drug delivery ability. Humans are the target of these systems, hence, animals whose systems resembles humans were used to predict outcome. Thus, increasing costs in money and time, plus ethical concerns over animal usage. However, with consideration and planning in experimental conditions, in vitro pharmacological studies of the nanodelivery can mimic the in vivo system. This can function as a simple method to investigate the effect of such materials without endangering animals especially at screening phase. BioMed Central 2014-07-16 /pmc/articles/PMC4108003/ /pubmed/25057288 http://dx.doi.org/10.1186/1752-153X-8-46 Text en Copyright © 2014 Kura et al.; licensee Chemistry Central Ltd. http://creativecommons.org/licenses/by/4.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Mini Review Kura, Aminu Umar Fakurazi, Sharida Hussein, Mohd Zobir Arulselvan, Palanisamy Nanotechnology in drug delivery: the need for more cell culture based studies in screening |
title | Nanotechnology in drug delivery: the need for more cell culture based studies in screening |
title_full | Nanotechnology in drug delivery: the need for more cell culture based studies in screening |
title_fullStr | Nanotechnology in drug delivery: the need for more cell culture based studies in screening |
title_full_unstemmed | Nanotechnology in drug delivery: the need for more cell culture based studies in screening |
title_short | Nanotechnology in drug delivery: the need for more cell culture based studies in screening |
title_sort | nanotechnology in drug delivery: the need for more cell culture based studies in screening |
topic | Mini Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108003/ https://www.ncbi.nlm.nih.gov/pubmed/25057288 http://dx.doi.org/10.1186/1752-153X-8-46 |
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