Randomized comparison of single dose of recombinant human IL-12 versus placebo for restoration of hematopoiesis and improved survival in rhesus monkeys exposed to lethal radiation

BACKGROUND: The hematopoietic syndrome of the acute radiation syndrome (HSARS) is a life-threatening condition in humans exposed to total body irradiation (TBI); no drugs are approved for treating this condition. Recombinant human interleukin-12 (rHuIL-12) is being developed for HSARS mitigation und...

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Detalles Bibliográficos
Autores principales: Gluzman-Poltorak, Zoya, Mendonca, Sarita R, Vainstein, Vladimir, Kha, Hue, Basile, Lena A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108131/
https://www.ncbi.nlm.nih.gov/pubmed/24708888
http://dx.doi.org/10.1186/1756-8722-7-31

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