A FluoPol-ABPP PAD2 High-Throughput Screen Identifies the First Calcium Site Inhibitor Targeting the PADs

[Image: see text] The protein arginine deiminases (PADs) catalyze the post-translational hydrolysis of peptidyl-arginine to form peptidyl-citrulline in a process termed deimination or citrullination. PADs likely play a role in the progression of a range of disease states because dysregulated PAD act...

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Detalles Bibliográficos
Autores principales: Lewallen, Daniel M., Bicker, Kevin L., Madoux, Franck, Chase, Peter, Anguish, Lynne, Coonrod, Scott, Hodder, Peter, Thompson, Paul R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108211/
https://www.ncbi.nlm.nih.gov/pubmed/24467619
http://dx.doi.org/10.1021/cb400841k

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108211/
https://www.ncbi.nlm.nih.gov/pubmed/24467619
http://dx.doi.org/10.1021/cb400841k

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