Cargando…

T-Cells Null for the MED23 Subunit of Mediator Express Decreased Levels of KLF2 and Inefficiently Populate the Peripheral Lymphoid Organs

MED23, a subunit of the Mediator coactivator complex, is important for the expression of a subset of MAPK/ERK pathway-responsive genes, the constituents of which vary between cell types for reasons that are not completely clear. MAPK/ERK pathway-dependent processes are essential for T-cell developme...

Descripción completa

Detalles Bibliográficos
Autores principales: Kasper, Lawryn H., Fukuyama, Tomofusa, Brindle, Paul K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108324/
https://www.ncbi.nlm.nih.gov/pubmed/25054639
http://dx.doi.org/10.1371/journal.pone.0102076