HIV-1 Specific IgA Detected in Vaginal Secretions of HIV Uninfected Women Participating in a Microbicide Trial in Southern Africa Are Primarily Directed Toward gp120 and gp140 Specificities

BACKGROUND: Many participants in microbicide trials remain uninfected despite ongoing exposure to HIV-1. Determining the emergence and nature of mucosal HIV-specific immune responses in such women is important, since these responses may contribute to protection and could provide insight for the rati...

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Detalles Bibliográficos
Autores principales: Seaton, Kelly E., Ballweber, Lamar, Lan, Audrey, Donathan, Michele, Hughes, Sean, Vojtech, Lucia, Moody, M. Anthony, Liao, Hua-Xin, Haynes, Barton F., Galloway, Christine G., Richardson, Barbra A., Karim, Salim Abdool, Dezzutti, Charlene S., McElrath, M. Juliana, Tomaras, Georgia D., Hladik, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108330/
https://www.ncbi.nlm.nih.gov/pubmed/25054205
http://dx.doi.org/10.1371/journal.pone.0101863

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