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Proteomic Characterization of Acyclovir-Induced Nephrotoxicity in a Mouse Model

Acyclovir (ACV) is an effective and widely used antiviral agent. However, its clinical application is limited by severe nephrotoxicity. We assessed ACV-induced nephrotoxicity and identified the differentially expressed proteins using mass spectrometry-based proteomic analysis. In total, 30 ICR mice...

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Detalles Bibliográficos
Autores principales: Lu, Hong, Han, Ya-Juan, Xu, Jia-Dong, Xing, Wen-Min, Chen, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108384/
https://www.ncbi.nlm.nih.gov/pubmed/25055032
http://dx.doi.org/10.1371/journal.pone.0103185

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