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Proteomic Characterization of Acyclovir-Induced Nephrotoxicity in a Mouse Model
Acyclovir (ACV) is an effective and widely used antiviral agent. However, its clinical application is limited by severe nephrotoxicity. We assessed ACV-induced nephrotoxicity and identified the differentially expressed proteins using mass spectrometry-based proteomic analysis. In total, 30 ICR mice...
Autores principales: | Lu, Hong, Han, Ya-Juan, Xu, Jia-Dong, Xing, Wen-Min, Chen, Jie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108384/ https://www.ncbi.nlm.nih.gov/pubmed/25055032 http://dx.doi.org/10.1371/journal.pone.0103185 |
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