LTX-315 (Oncopore™): A short synthetic anticancer peptide and novel immunotherapeutic agent

Several cationic antimicrobial peptides demonstrate promising anticancer effects. We have recently described the anticancer properties of LTX-315, a novel synthetic anticancer peptide, against syngeneic B16 melanomas. LTX-315 induced a complete regression of B16 melanomas and systemic protective imm...

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Detalles Bibliográficos
Autores principales: Camilio, Ketil André, Rekdal, Øystein, Sveinbjörnsson, Baldur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108458/
https://www.ncbi.nlm.nih.gov/pubmed/25083333
http://dx.doi.org/10.4161/onci.29181
Descripción
Sumario:Several cationic antimicrobial peptides demonstrate promising anticancer effects. We have recently described the anticancer properties of LTX-315, a novel synthetic anticancer peptide, against syngeneic B16 melanomas. LTX-315 induced a complete regression of B16 melanomas and systemic protective immune responses following intralesional administration of the peptide.

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