Cargando…
mTOR and lysosome regulation
Lysosomes are key cellular organelles that play a crucial role in catabolism by degrading extracellular and intracellular material. It is, therefore, very intriguing that mTORC1 (mechanistic target of rapamycin complex 1), a major promoter of anabolic processes, localizes in its active form to the s...
Autor principal: | Puertollano, Rosa |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Faculty of 1000 Ltd
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108950/ https://www.ncbi.nlm.nih.gov/pubmed/25184042 http://dx.doi.org/10.12703/P6-52 |
Ejemplares similares
-
The mTOR–lysosome axis at the centre of ageing
por: Carosi, Julian M., et al.
Publicado: (2021) -
Autophagy termination and lysosome reformation regulated by mTOR
por: Yu, Li, et al.
Publicado: (2010) -
A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB
por: Settembre, Carmine, et al.
Publicado: (2012) -
Modulation of mTOR signaling as a strategy for the treatment of Pompe disease
por: Lim, Jeong‐A, et al.
Publicado: (2017) -
Ubiquilins Regulate Autophagic Flux through mTOR Signaling and Lysosomal Acidification
por: Şentürk, Mümine, et al.
Publicado: (2019)